Malaria continues to impose enormous health and economic burdens on the developing world. Novel technologies proposed to reduce the impact of the disease include the introgression of parasite-resistance genes into mosquito populations, thereby modifying the ability of the vector to transmit the pathogens. Such genes have been developed for the human malaria parasite Plasmodium falciparum. Here we provide evidence for a highly efficient gene-drive system that can spread these antimalarial genes into a target vector population.
Twenty years ago, the first genetically modified (GM) crops were planted in the USA, alongside dazzling promises about this new technology. Two decades on, the promises are getting bigger and bigger, but GM crops are not delivering any of them.