The objective of the study was to identify mechanisms for cancer resistance in elephants and compare cellular response to DNA damage among elephants, healthy human controls, and cancer-prone patients with Li-Fraumeni syndrome (LFS).

The past was a world of giants, with abundant whales in the sea and large animals roaming the land. However, that world came to an end following massive late-Quaternary megafauna extinctions on land and widespread population reductions in great whale populations over the past few centuries. These losses are likely to have had important consequences for broad-scale nutrient cycling, because recent literature suggests that large animals disproportionately drive nutrient movement.

Metrics that synthesize the complex effects of climate change are essential tools for mapping future threats to biodiversity and predicting which species are likely to adapt in place to new climatic conditions, disperse and establish in areas with newly suitable climate, or face the prospect of extirpation. The most commonly used of such metrics is the velocity of climate change, which estimates the speed at which species must migrate over the earth’s surface to maintain constant climatic conditions.

Following the 1986 Chernobyl accident, 116,000 people were permanently evacuated from the 4,200 km Chernobyl exclusion zone. There is continuing scientific and public debate surrounding the fate of wildlife that remained in the abandoned area. Several previous studies of the Chernobyl exclusion zone indicated major radiation effects and pronounced reductions in wildlife populations at dose rates well below those thought to cause significant impacts. In contrast, our long-term empirical data showed no evidence of a negative influence of radiation on mammal abundance.

Many captive populations of birds and mammals are not likely to reach sustainability due mostly to breeding problems. Identifying the conditions under which breeding problems and poor population growth are likely to occur and establishing more appropriate conditions, therefore, will be a necessary prerequisite for future successful conservation breeding and the long-term survival of captive populations. This article analyses the basic approaches and concepts of management programmes for captive mammals.