Climate change is one of the most important environmental, social and economic issues facing the world today. Some impacts such as increasing heat stress, more intense floods, droughts, and rising sea levels have now become inevitable. The impacts are most severe for the global poor, and South Asia is one of the regions affected by the changes. We must plan and adapt to minimize the negative impacts and enhance human and ecosystem welfare. Climate innovation and technologies involve basic science and engineering as well as information dissemination, capacity building, and community organizing.