Mitochondrial dysfunction has been implicated in the pathogenesis of a variety of disorders including cancer, diabetes, and neurodegenerative and cardiovascular diseases. Understanding whether different environmental chemicals and drug-like molecules impact mitochondrial function represents an initial step in predicting exposure-related toxicity and defining a possible role for such compounds in the onset of various diseases.
Links:
[1] http://admin.indiaenvironmentportal.org.in/feature-article/profiling-tox21-chemical-collection-mitochondrial-function-identify-compounds
[2] http://admin.indiaenvironmentportal.org.in/category/author/matias-s-attene-ramos
[3] http://admin.indiaenvironmentportal.org.in/category/author/ruili-huang
[4] http://admin.indiaenvironmentportal.org.in/category/author/sam-michael-et-al
[5] http://admin.indiaenvironmentportal.org.in/category/journal/environmental-health-perspectives
[6] http://admin.indiaenvironmentportal.org.in/category/thesaurus/toxins
[7] http://admin.indiaenvironmentportal.org.in/category/thesaurus/health-effects
[8] http://admin.indiaenvironmentportal.org.in/category/thesaurus/toxicity-studies