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Home > Featured Articles > Profiling of the Tox21 chemical collection for mitochondrial function to identify compounds that acutely decrease mitochondrial membrane potential > Profiling of the Tox21 chemical collection for mitochondrial function to identify compounds that acutely decrease mitochondrial membrane potential

Profiling of the Tox21 chemical collection for mitochondrial function to identify compounds that acutely decrease mitochondrial membrane potential [1]

Mitochondrial dysfunction has been implicated in the pathogenesis of a variety of disorders including cancer, diabetes, and neurodegenerative and cardiovascular diseases. Understanding whether different environmental chemicals and drug-like molecules impact mitochondrial function represents an initial step in predicting exposure-related toxicity and defining a possible role for such compounds in the onset of various diseases.

Publication Date: 
10/10/2014
Matias S. Attene-Ramos [2], Ruili Huang [3], Sam Michael & et al [4]
Environmental Health Perspectives [5]
1-31
Tags:
Toxins [6], Health Effects [7], Toxicity Studies [8]
Centre for Science and Environment
National Knowledge Commission Government of India

Technology Partners: MimirTech


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Source URL: http://admin.indiaenvironmentportal.org.in/feature-article/profiling-tox21-chemical-collection-mitochondrial-function-identify-compounds

Links:
[1] http://admin.indiaenvironmentportal.org.in/feature-article/profiling-tox21-chemical-collection-mitochondrial-function-identify-compounds
[2] http://admin.indiaenvironmentportal.org.in/category/author/matias-s-attene-ramos
[3] http://admin.indiaenvironmentportal.org.in/category/author/ruili-huang
[4] http://admin.indiaenvironmentportal.org.in/category/author/sam-michael-et-al
[5] http://admin.indiaenvironmentportal.org.in/category/journal/environmental-health-perspectives
[6] http://admin.indiaenvironmentportal.org.in/category/thesaurus/toxins
[7] http://admin.indiaenvironmentportal.org.in/category/thesaurus/health-effects
[8] http://admin.indiaenvironmentportal.org.in/category/thesaurus/toxicity-studies