Telomere length and mitochondrial DNA (mtDNA) content are markers of aging and aging-related diseases. There is inconclusive evidence concerning the mechanistic effects of airborne particulate matter (PM) exposure on biomolecular markers of ageing. The present study examines the association between short- and long-term PM exposure with telomere length and mtDNA content in elderly and investigates to what extend this association is mediated by expression of genes playing a role in the telomere-mitochondrial axis of aging.
Original Source [2]
Technology Partners: MimirTech
Links:
[1] http://admin.indiaenvironmentportal.org.in/feature-article/biomolecular-markers-within-core-axis-aging-and-particulate-air-pollution-exposure
[2] http://http://ehp.niehs.nih.gov/wp-content/uploads/advpub/2015/12/ehp.1509728.acco.pdf
[3] http://admin.indiaenvironmentportal.org.in/category/author/nicky-pieters
[4] http://admin.indiaenvironmentportal.org.in/category/author/bram-g-janssen
[5] http://admin.indiaenvironmentportal.org.in/category/author/harrie-dewitte-et-al
[6] http://admin.indiaenvironmentportal.org.in/category/journal/environmental-health-perspectives
[7] http://admin.indiaenvironmentportal.org.in/category/thesaurus/air-pollution
[8] http://admin.indiaenvironmentportal.org.in/category/thesaurus/health-effects
[9] http://admin.indiaenvironmentportal.org.in/category/thesaurus/aged
[10] http://admin.indiaenvironmentportal.org.in/category/thesaurus/pm-25
[11] http://admin.indiaenvironmentportal.org.in/category/thesaurus/air-quality-and-health
