This How to Do Note (HTDN) is intended to provide guidance on how to design smallholder agriculture adaptation programmes that consider the differential impacts of climate change on women, men and youth smallholder farmers. This includes recognizing that programme interventions – from design to staffing to capacity development of beneficiaries and local organizations – need to consider how gender will affect sustainability and impact. The experiences, social positions and differing access to resources of marginalized populations are fundamental considerations in the design, implementation, and monitoring and evaluation of gender transformative smallholder agriculture adaptation programmes.