Confocal laser endomicroscopy (pCLE) provides real-time histologic imaging of human tissues at a depth of 60–70 μm during endoscopy. pCLE of the extrahepatic bile duct after fluorescein injection demonstrated a reticular pattern within fluorescein-filled sinuses that had no known anatomical correlate. Freezing biopsy tissue before fixation preserved the anatomy of this structure, demonstrating that it is part of the submucosa and a previously unappreciated fluid-filled interstitial space, draining to lymph nodes and supported by a complex network of thick collagen bundles.
Original Source [2]
Links:
[1] http://admin.indiaenvironmentportal.org.in/feature-article/structure-and-distribution-unrecognized-interstitium-human-tissues
[2] https://www.nature.com/articles/s41598-018-23062-6
[3] http://admin.indiaenvironmentportal.org.in/category/author/petros-c-benias
[4] http://admin.indiaenvironmentportal.org.in/category/author/rebecca-g-wells
[5] http://admin.indiaenvironmentportal.org.in/category/author/bridget-sackey-aboagye-et-al
[6] http://admin.indiaenvironmentportal.org.in/category/journal/scientific-reports
[7] http://admin.indiaenvironmentportal.org.in/category/thesaurus/health
[8] http://admin.indiaenvironmentportal.org.in/category/thesaurus/research
[9] http://admin.indiaenvironmentportal.org.in/category/thesaurus/diseases