Chlorpyrifos (CPF), a widely used organophosphorus pesticide (OP), is metabolized to CPF-oxon, a potent cholinesterase (ChE) inhibitor, and trichloro-2-pyridinol (TCPy). Urinary TCPy is often used as a biomarker for CPF exposure, whereas blood ChE activity is considered an indicator of CPF toxicity. However, whether these biomarkers are dose related has not been studied extensively in populations with repeated daily OP exposures. The authors sought to determine the relationship between blood ChE and urinary TCPy during repeated occupational exposures to CPF.
Technology Partners: MimirTech
Links:
[1] http://admin.indiaenvironmentportal.org.in/feature-article/biomarkers-chlorpyrifos-exposure-and-effect-egyptian-cotton-field-workers
[2] http://admin.indiaenvironmentportal.org.in/category/author/fayssal-m-farahat
[3] http://admin.indiaenvironmentportal.org.in/category/author/corie-ellison
[4] http://admin.indiaenvironmentportal.org.in/category/author/matthew-r-bonner-et-al
[5] http://admin.indiaenvironmentportal.org.in/category/journal/environmental-health-perspectives
[6] http://admin.indiaenvironmentportal.org.in/category/thesaurus/chlorpyriphos
[7] http://admin.indiaenvironmentportal.org.in/category/thesaurus/egypt
[8] http://admin.indiaenvironmentportal.org.in/category/thesaurus/cotton
[9] http://admin.indiaenvironmentportal.org.in/category/thesaurus/pesticide-use
[10] http://admin.indiaenvironmentportal.org.in/category/thesaurus/agriculture
[11] http://admin.indiaenvironmentportal.org.in/category/thesaurus/occupational-health
[12] http://admin.indiaenvironmentportal.org.in/category/thesaurus/health-effects
