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Home > Featured Articles > MicroRNA expression in response to controlled exposure to diesel exhaust: Attenuation by the antioxidant n-acetylcysteine in a randomized crossover study > MicroRNA expression in response to controlled exposure to diesel exhaust: Attenuation by the antioxidant n-acetylcysteine in a randomized crossover study

MicroRNA expression in response to controlled exposure to diesel exhaust: Attenuation by the antioxidant n-acetylcysteine in a randomized crossover study [1]

Health effects associated with diesel exhaust (DE) are thought to be mediated in part by oxidative stress, but the detailed mechanisms therein are largely unknown. MicroRNAs (miRNAs) regulate gene expression post­transcriptionally and may respond to exposures such as DE. The researchers profiled peripheral blood cellular miRNAs in mild asthmatic participants exposed to controlled DE with and without antioxidant supplementation.

Original Source [2]

Publication Date: 
12/04/2013
Masatsugu Yamamoto [3], Amrit Singh [4], Francesco Sava & et al [5]
Environmental Health Perspectives [6]
1-31
Tags:
Diesel [7], Health Effects [8], Asthma [9], Respiratory Diseases [10], Vehicular Pollution [11], Canada [12]
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Source URL: http://admin.indiaenvironmentportal.org.in/feature-article/microrna-expression-response-controlled-exposure-diesel-exhaust-attenuation

Links:
[1] http://admin.indiaenvironmentportal.org.in/feature-article/microrna-expression-response-controlled-exposure-diesel-exhaust-attenuation
[2] http://ehp.niehs.nih.gov/1205963/
[3] http://admin.indiaenvironmentportal.org.in/category/author/masatsugu-yamamoto
[4] http://admin.indiaenvironmentportal.org.in/category/author/amrit-singh
[5] http://admin.indiaenvironmentportal.org.in/category/author/francesco-sava-et-al
[6] http://admin.indiaenvironmentportal.org.in/category/journal/environmental-health-perspectives
[7] http://admin.indiaenvironmentportal.org.in/category/thesaurus/diesel
[8] http://admin.indiaenvironmentportal.org.in/category/thesaurus/health-effects
[9] http://admin.indiaenvironmentportal.org.in/category/thesaurus/asthma
[10] http://admin.indiaenvironmentportal.org.in/category/thesaurus/respiratory-diseases
[11] http://admin.indiaenvironmentportal.org.in/category/thesaurus/vehicular-pollution
[12] http://admin.indiaenvironmentportal.org.in/category/thesaurus/canada