A variety of chemicals are used in cosmetics as ingredients and some are used as preservatives. These chemicals have different health effects. Hexavallent Chromium (Cr+6) is corrosive and allergic to the skin. Cr+6 compounds are enlisted as carcinogens by the International Agency for Research on Cancer (IARC). Adverse effects of the Cr+6 on the skin may include ulcerations, dermatitis, and allergic skin reactions. Inhalation of Cr+6 compounds can result in ulceration and perforation of the mucous membranes of the nasal septum, irritation of the pharynx and larynx, asthmatic bronchitis, bronchospasms and edema. Respiratory symptoms may include coughing and wheezing, shortness of breath, and nasal itch.