HIV persists in a small pool of latently infected cells despite antiretroviral therapy (ART). Identifying cellular markers expressed at the surface of these cells may lead to novel therapeutic strategies to reduce the size of the HIV reservoir. We hypothesized that CD4+ T cells expressing immune checkpoint molecules would be enriched in HIV-infected cells in individuals receiving suppressive ART.
Original Source [2]
Technology Partners: MimirTech
Links:
[1] http://admin.indiaenvironmentportal.org.in/feature-article/cd4-t-cells-expressing-pd-1-tigit-and-lag-3-contribute-hiv-persistence-during-art
[2] http://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1005761
[3] http://admin.indiaenvironmentportal.org.in/category/author/r%C3%A9mi-fromentin
[4] http://admin.indiaenvironmentportal.org.in/category/author/wendy-bakeman
[5] http://admin.indiaenvironmentportal.org.in/category/author/mariam-b-lawani-et-al
[6] http://admin.indiaenvironmentportal.org.in/category/journal/plos-pathogens
[7] http://admin.indiaenvironmentportal.org.in/category/thesaurus/aids
[8] http://admin.indiaenvironmentportal.org.in/category/thesaurus/medical-research
[9] http://admin.indiaenvironmentportal.org.in/category/thesaurus/drugs
