Cutaneous granulomas are a well-recognized pathologic feature in patients with various primary immunodeficiency diseases (PIDs) and may be self-limited or can progress to a persisting granulomatous disorder.1,2 Rubella virus (RV) vaccine strain RA27/3 has been recently detected in disseminated cutaneous granulomas of 2 patients with ataxia telangiectasia (AT) and a patient with Simpson-Golabi-Behmel syndrome (who had combined immunodeficiency [CID]).3 However, a more detailed study of a larger series of granuloma cases in patients with different PIDs was required to confirm and extend this observation.
Original Source [2]
Technology Partners: MimirTech
Links:
[1] http://admin.indiaenvironmentportal.org.in/feature-article/rubella-persistence-epidermal-keratinocytes-and-granuloma-m2-macrophages-patients
[2] http://www.jacionline.org/article/S0091-6749(16)30712-6/pdf
[3] http://admin.indiaenvironmentportal.org.in/category/author/ludmila-perelygina
[4] http://admin.indiaenvironmentportal.org.in/category/author/stanley-plotkin
[5] http://admin.indiaenvironmentportal.org.in/category/author/pierre-russo-et-al
[6] http://admin.indiaenvironmentportal.org.in/category/journal/journal-allergy-and-clinical-immunology
[7] http://admin.indiaenvironmentportal.org.in/category/thesaurus/vaccination
[8] http://admin.indiaenvironmentportal.org.in/category/thesaurus/viral-diseases
[9] http://admin.indiaenvironmentportal.org.in/category/thesaurus/measles
[10] http://admin.indiaenvironmentportal.org.in/category/thesaurus/health-effects
[11] http://admin.indiaenvironmentportal.org.in/category/thesaurus/drugs
