Population genetics of Vibrio cholerae from Nepal in 2010: Evidence on the origin of the Haitian outbreak

Population genetics of Vibrio cholerae from Nepal in 2010: Evidence on the origin of the Haitian outbreak [1]

Cholera continues to be an important cause of human infections, and outbreaks are often observed after natural disasters, such as the one following the 2010 earthquake in Haiti. Once the cholera outbreak was conﬁrmed, rumors spread that
the disease was brought to Haiti by a battalion of Nepalese soldiers serving as United Nations peacekeepers. This possible connection has never been conﬁrmed. We used whole-genome sequence typing (WGST), pulsed-ﬁeld gel electrophoresis (PFGE), and antimicrobial susceptibility testing to characterize 24 recentVibrio cholerae isolates from Nepal and evaluate the suggested epidemiological link with the Haitian outbreak. The isolates were obtained from 30 July to 1 November 2010 from ﬁve different districts in Nepal. We compared the 24 genomes to 10 previously sequencedV. cholerae isolates, including 3 from the Haitian outbreak (began July 2010).

Publication Date:

01/07/2011

Author(s): Rene S. Hendriksen [2], Lance B. Price [3], James M. Schupp & et al [4]

Source: mBio [5]

Vol:

Issue:

pp:

1-6

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