Dengue virus infection has recently taken endemic proportions in India with dengu type-3 (DEN-3) as a predominant serotype. In this study, we carried out the selection pressure analysis of three critical immunogenic
regions of DEN-3. Phylogenetic analysis was then carried out on the positively selected genomic region in the DEN-3 virus strains isolated in the Indian subcontinent over a time span of 25 yr (1984–2008). Bayesian Markov chain Monte Carlo (MCMC) calculation of the substitution rate was carried out for the DEN-3 genotype-III sequences.
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Links:
[1] http://admin.indiaenvironmentportal.org.in/feature-article/positive-selection-and-evolution-dengue-type-3-virus-indian-subcontinent
[2] http://admin.indiaenvironmentportal.org.in/category/author/sukhmani-k-bedi
[3] http://admin.indiaenvironmentportal.org.in/category/author/apar-prasad
[4] http://admin.indiaenvironmentportal.org.in/category/author/krishanu-mathur-et-al
[5] http://admin.indiaenvironmentportal.org.in/category/journal/journal-vector-borne-diseases
[6] http://admin.indiaenvironmentportal.org.in/category/thesaurus/dengue
[7] http://admin.indiaenvironmentportal.org.in/category/thesaurus/india
[8] http://admin.indiaenvironmentportal.org.in/category/thesaurus/vector-borne-diseases
[9] http://admin.indiaenvironmentportal.org.in/category/thesaurus/delhi
