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Home > Featured Articles > Treatment outcomes for patients with extensively drug-resistant Tuberculosis, KwaZulu-Natal and Eastern Cape Provinces, South Africa > Treatment outcomes for patients with extensively drug-resistant Tuberculosis, KwaZulu-Natal and Eastern Cape Provinces, South Africa

Treatment outcomes for patients with extensively drug-resistant Tuberculosis, KwaZulu-Natal and Eastern Cape Provinces, South Africa [1]

The researchers analyzed data for a retrospective cohort of patients treated for extensively drug-resistant tuberculosis in 2 provinces in South Africa and compared predictors of treatment outcome in HIV-positive patients who received or had not received antiretroviral drugs with those for HIV-negative patients. Overall, 220 (62.0%) of 355 patients were HIV positive. After 2 years, 34 (10.3%) of 330 patients with a known HIV status and known outcome had a favorable outcome. Multivariate analysis showed that predictors of favorable outcome were negative results for acid-fast bacilli by sputum microscopy at start of treatment and weight >50 kg.

Original Source [2]

Publication Date: 
01/09/2016
Charlotte L. Kvasnovsky [3], J. Peter Cegielski [4], Martie L. van der Walt [5]
Emerging Infectious Diseases [6]
22
9
1529-1536
Tags:
Tuberculosis [7], South Africa [8], AIDS [9], Drugs [10], Research [11]
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Source URL: http://admin.indiaenvironmentportal.org.in/feature-article/treatment-outcomes-patients-extensively-drug-resistant-tuberculosis-kwazulu-natal

Links:
[1] http://admin.indiaenvironmentportal.org.in/feature-article/treatment-outcomes-patients-extensively-drug-resistant-tuberculosis-kwazulu-natal
[2] http://wwwnc.cdc.gov/eid/article/22/9/pdfs/16-0084.pdf
[3] http://admin.indiaenvironmentportal.org.in/category/author/charlotte-l-kvasnovsky
[4] http://admin.indiaenvironmentportal.org.in/category/author/j-peter-cegielski
[5] http://admin.indiaenvironmentportal.org.in/category/author/martie-l-van-der-walt
[6] http://admin.indiaenvironmentportal.org.in/category/journal/emerging-infectious-diseases
[7] http://admin.indiaenvironmentportal.org.in/category/thesaurus/tuberculosis
[8] http://admin.indiaenvironmentportal.org.in/category/thesaurus/south-africa
[9] http://admin.indiaenvironmentportal.org.in/category/thesaurus/aids
[10] http://admin.indiaenvironmentportal.org.in/category/thesaurus/drugs
[11] http://admin.indiaenvironmentportal.org.in/category/thesaurus/research