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Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity [1]

Approximately 1.5 billion people worldwide are overweight or affected by obesity, and are at risk of developing type 2 diabetes, cardiovascular disease and related metabolic and inflammatory disturbances. Although the mechanisms linking adiposity to associated clinical conditions are poorly understood, recent studies suggest that adiposity may influence DNA methylation, a key regulator of gene expression and molecular phenotype.

Publication Date: 
05/01/2017
Simone Wahl [2], Alexander Drong [3], Benjamin Lehne & et al [4]
Nature [5]
541
81-86
Tags:
Obesity [6], Non Communicable Diseases [7], Medical Research [8]

Technology Partners: MimirTech

Source URL: http://admin.indiaenvironmentportal.org.in/feature-article/epigenome-wide-association-study-body-mass-index-and-adverse-outcomes-adiposity

Links:
[1] http://admin.indiaenvironmentportal.org.in/feature-article/epigenome-wide-association-study-body-mass-index-and-adverse-outcomes-adiposity
[2] http://admin.indiaenvironmentportal.org.in/category/author/simone-wahl
[3] http://admin.indiaenvironmentportal.org.in/category/author/alexander-drong
[4] http://admin.indiaenvironmentportal.org.in/category/author/benjamin-lehne-et-al
[5] http://admin.indiaenvironmentportal.org.in/category/journal/nature
[6] http://admin.indiaenvironmentportal.org.in/category/thesaurus/obesity
[7] http://admin.indiaenvironmentportal.org.in/category/thesaurus/non-communicable-diseases
[8] http://admin.indiaenvironmentportal.org.in/category/thesaurus/medical-research