The tumor microenvironment plays in an important role in the progression of cancer by mediating stromal-epithelial paracrine signaling, which can aberrantly modulate cellular proliferation and tumorigenesis. Exposure to environmental toxicants, such as inorganic arsenic (iAs), has also been implicated in the progression of prostate cancer.
Original Source [2]
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Links:
[1] http://admin.indiaenvironmentportal.org.in/feature-article/inorganic-arsenic-related-changes-stromal-tumor-microenvironment-prostate-cancer
[2] http://ehp.niehs.nih.gov/15-10090/
[3] http://admin.indiaenvironmentportal.org.in/category/author/joseph-j-shearer
[4] http://admin.indiaenvironmentportal.org.in/category/author/eric-wold
[5] http://admin.indiaenvironmentportal.org.in/category/author/charles-s-umbaugh-et-al
[6] http://admin.indiaenvironmentportal.org.in/category/journal/environmental-health-perspectives
[7] http://admin.indiaenvironmentportal.org.in/category/thesaurus/arsenic
[8] http://admin.indiaenvironmentportal.org.in/category/thesaurus/cancer
[9] http://admin.indiaenvironmentportal.org.in/category/thesaurus/research
