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Home > Featured Articles > Public health impact and cost-effectiveness of the RTS,S/AS01 malaria vaccine: a systematic comparison of predictions from four mathematical models > Public health impact and cost-effectiveness of the RTS,S/AS01 malaria vaccine: a systematic comparison of predictions from four mathematical models

Public health impact and cost-effectiveness of the RTS,S/AS01 malaria vaccine: a systematic comparison of predictions from four mathematical models [1]

The phase 3 trial of the RTS,S/AS01 malaria vaccine candidate showed modest efficacy of the vaccine against Plasmodium falciparum malaria, but was not powered to assess mortality endpoints. Impact projections and cost-effectiveness estimates for longer timeframes than the trial follow-up and across a range of settings are needed to inform policy recommendations. We aimed to assess the public health impact and cost-effectiveness of routine use of the RTS,S/AS01 vaccine in African settings.

Original Source [2]

Publication Date: 
23/01/2016
Melissa A Penny [3], Robert Verity [4], Caitlin A Bever & et al [5]
Lancet [6]
387
10016
367–375
Tags:
Malaria [7], Drugs [8], Public Sector [9], Private Sector [10], Child Health [11], Vaccination [12], Vector Borne Diseases [13], Africa [14], Medical Research [15]
Centre for Science and Environment
National Knowledge Commission Government of India

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Source URL: http://admin.indiaenvironmentportal.org.in/feature-article/public-health-impact-and-cost-effectiveness-rtssas01-malaria-vaccine-systematic

Links:
[1] http://admin.indiaenvironmentportal.org.in/feature-article/public-health-impact-and-cost-effectiveness-rtssas01-malaria-vaccine-systematic
[2] http://www.lancet.com/journals/lancet/article/PIIS0140-6736(15)00725-4/abstract
[3] http://admin.indiaenvironmentportal.org.in/category/author/melissa-penny
[4] http://admin.indiaenvironmentportal.org.in/category/author/robert-verity
[5] http://admin.indiaenvironmentportal.org.in/category/author/caitlin-bever-et-al
[6] http://admin.indiaenvironmentportal.org.in/category/journal/lancet
[7] http://admin.indiaenvironmentportal.org.in/category/thesaurus/malaria
[8] http://admin.indiaenvironmentportal.org.in/category/thesaurus/drugs
[9] http://admin.indiaenvironmentportal.org.in/category/thesaurus/public-sector
[10] http://admin.indiaenvironmentportal.org.in/category/thesaurus/private-sector
[11] http://admin.indiaenvironmentportal.org.in/category/thesaurus/child-health
[12] http://admin.indiaenvironmentportal.org.in/category/thesaurus/vaccination
[13] http://admin.indiaenvironmentportal.org.in/category/thesaurus/vector-borne-diseases
[14] http://admin.indiaenvironmentportal.org.in/category/thesaurus/africa
[15] http://admin.indiaenvironmentportal.org.in/category/thesaurus/medical-research