Researchers identified a novel plasmid-mediated colistin-resistance gene in porcine and bovine colistin-resistant Escherichia coli that did not contain mcr-1. The gene, termed mcr-2, a 1,617 bp phosphoethanolamine transferase harboured on an IncX4 plasmid, has 76.7% nucleotide identity to mcr-1. Prevalence of mcr-2 in porcine colistin-resistant E. coli (11/53) in Belgium was higher than that of mcr-1 (7/53). These data call for an immediate introduction of mcr-2 screening in ongoing molecular epidemiological surveillance of colistin-resistant Gram-negative pathogens.
Original Source [2]
Technology Partners: MimirTech
Links:
[1] http://admin.indiaenvironmentportal.org.in/feature-article/identification-novel-plasmid-mediated-colistin-resistance-gene-mcr-2-inescherichia
[2] http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=22525
[3] http://admin.indiaenvironmentportal.org.in/category/author/b-b-xavier
[4] http://admin.indiaenvironmentportal.org.in/category/author/c-lammens
[5] http://admin.indiaenvironmentportal.org.in/category/author/r-ruhal-et-al
[6] http://admin.indiaenvironmentportal.org.in/category/journal/eurosurveillance
[7] http://admin.indiaenvironmentportal.org.in/category/thesaurus/animal-diseases
[8] http://admin.indiaenvironmentportal.org.in/category/thesaurus/micro-organisms
[9] http://admin.indiaenvironmentportal.org.in/category/thesaurus/belgium
[10] http://admin.indiaenvironmentportal.org.in/category/thesaurus/livestock
[11] http://admin.indiaenvironmentportal.org.in/category/thesaurus/pigs
