Biotechnology is a knowledge intensive sector and this state is proud of producing relevant state of the art knowledge. Presence of Bengal and its diasporas can be easily identified, specially within the knowledge generation parts of BT sector, at both national and global level. The universities and research institutions located within the State are greatly contributing towards this goal. The strategy to develop a viable and vibrant biotechnology based industry, economy and a beneficiary social sector will depend on focus and attention in bringing various differentiated and specialized knowledge, skills, management, and investment partners together. The current policy of BT in West Bengal State is to bring this essential developmental agenda into focus and facilitate its translation for the inclusive benefits of this state. The constraints and challenges which hinder such development will be identified and rectified.