The Polio Eradication and Endgame Strategic Plan 2013–2018 is a comprehensive, long-term strategy that addresses what is needed to deliver a polio-free world by 2018. The plan was developed by the Global Polio Eradication Initiative (GPEI) in consultation with national health authorities, global health initiatives, scientific experts, donors and other stakeholders, in response to a directive of the World Health Assembly. The Polio Eradication and Endgame Strategic Plan 2013-2018 addresses the eradication of all polio disease, whether caused by wild poliovirus or circulating vaccine-derived poliovirus, while planning for the backbone of the polio effort to be used for delivering other health services to the world’s most vulnerable children.