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Home > Featured Articles > Visceral Leishmaniasis and HIV co-infection in Bihar, India: Long-term effectiveness and treatment outcomes with Liposomal Amphotericin B (AmBisome) > Visceral Leishmaniasis and HIV co-infection in Bihar, India: Long-term effectiveness and treatment outcomes with Liposomal Amphotericin B (AmBisome)

Visceral Leishmaniasis and HIV co-infection in Bihar, India: Long-term effectiveness and treatment outcomes with Liposomal Amphotericin B (AmBisome) [1]

Visceral Leishmaniasis (VL; also known as kala-azar) is an ultimately fatal disease endemic in the Indian state of Bihar, while HIV/AIDS is an emerging disease in this region. A 2011 observational cohort study conducted in Bihar involving 55 VL/HIV co-infected patients treated with 20–25 mg/kg intravenous liposomal amphotericin B (AmBisome) estimated an 85.5% probability of survival and a 26.5% probability of VL relapse within 2 years. Here we report the long-term field outcomes of a larger cohort of co-infected patients treated with this regimen between 2007 and 2012.

Publication Date: 
28/08/2014
Sakib Burza [2], Raman Mahajan [3], Prabhat K. Sinha & et al [4]
PLoS Neglected Tropical Diseases [5]
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Tags:
Kala Azar [6], AIDS [7], Bihar [8], Health Care [9], Infectious Diseases [10], India [11]
Centre for Science and Environment
National Knowledge Commission Government of India

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Links:
[1] http://admin.indiaenvironmentportal.org.in/feature-article/visceral-leishmaniasis-and-hiv-co-infection-bihar-india-long-term-effectiveness-and
[2] http://admin.indiaenvironmentportal.org.in/category/author/sakib-burza
[3] http://admin.indiaenvironmentportal.org.in/category/author/raman-mahajan
[4] http://admin.indiaenvironmentportal.org.in/category/author/prabhat-k-sinha-et-al
[5] http://admin.indiaenvironmentportal.org.in/category/journal/plos-neglected-tropical-diseases
[6] http://admin.indiaenvironmentportal.org.in/category/thesaurus/kala-azar
[7] http://admin.indiaenvironmentportal.org.in/category/thesaurus/aids
[8] http://admin.indiaenvironmentportal.org.in/category/thesaurus/bihar
[9] http://admin.indiaenvironmentportal.org.in/category/thesaurus/health-care
[10] http://admin.indiaenvironmentportal.org.in/category/thesaurus/infectious-diseases
[11] http://admin.indiaenvironmentportal.org.in/category/thesaurus/india