WHO recommends combinations of an artemisinin derivative plus an antimalarial drug of longer half-life as treatment options for uncomplicated Plasmodium falciparum infection. In Africa, artemether–lumefantrine is the most widely used artemisinin-based combination therapy, whereas artesunate–mefl oquine is used infrequently because of a perceived poor tolerance to mefl oquine. WHO recommends reconsideration of the use of artesunate– mefl oquine in Africa. We compared the effi cacy and safety of fi xed-dose artesunate–mefl oquine with that of artemether– lumefantrine for treatment of children younger than 5 years with uncomplicated P falciparum malaria.
Original Source [2]
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Links:
[1] http://admin.indiaenvironmentportal.org.in/feature-article/comparison-artesunate%E2%80%93mefloquine-and-artemether%E2%80%93lumefantrine-fixed-dose-combinations
[2] http://www.thelancet.com/pdfs/journals/laninf/PIIS1473-3099(16)30020-2.pdf
[3] http://admin.indiaenvironmentportal.org.in/category/author/sodiomon-b-sirima
[4] http://admin.indiaenvironmentportal.org.in/category/author/bernhards-ogutu
[5] http://admin.indiaenvironmentportal.org.in/category/author/john-p-lusingu-et-al
[6] http://admin.indiaenvironmentportal.org.in/category/journal/lancet
[7] http://admin.indiaenvironmentportal.org.in/category/thesaurus/malaria
[8] http://admin.indiaenvironmentportal.org.in/category/thesaurus/africa
[9] http://admin.indiaenvironmentportal.org.in/category/thesaurus/drugs
[10] http://admin.indiaenvironmentportal.org.in/category/thesaurus/child-health
[11] http://admin.indiaenvironmentportal.org.in/category/thesaurus/burkina-faso
[12] http://admin.indiaenvironmentportal.org.in/category/thesaurus/kenya
[13] http://admin.indiaenvironmentportal.org.in/category/thesaurus/tanzania
[14] http://admin.indiaenvironmentportal.org.in/category/thesaurus/medical-research
