Antibiotic resistance among enterococci and γ-proteobacteria is an increasing problem in healthcare settings. Dense colonization of the gut by antibiotic-resistant bacteria facilitates their spread between patients and also leads to bloodstream and other systemic infections. Antibiotic-mediated destruction of the intestinal microbiota and consequent loss of colonization resistance are critical factors leading to persistence and spread of antibiotic-resistant bacteria. The mechanisms underlying microbiota-mediated colonization resistance remain incompletely defined and are likely distinct for different antibiotic-resistant bacterial species. It is unclear whether enterococci or γ-proteobacteria, upon expanding to high density in the gut, confer colonization resistance against competing bacterial species.
Original Source [2]
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Links:
[1] http://admin.indiaenvironmentportal.org.in/feature-article/distinct-spatially-overlapping-intestinal-niches-vancomycin-resistant-enterococcus
[2] http://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1005132
[3] http://admin.indiaenvironmentportal.org.in/category/author/silvia-caballero
[4] http://admin.indiaenvironmentportal.org.in/category/author/rebecca-carter
[5] http://admin.indiaenvironmentportal.org.in/category/author/xu-ke-et-al
[6] http://admin.indiaenvironmentportal.org.in/category/journal/plos-pathogens
[7] http://admin.indiaenvironmentportal.org.in/category/thesaurus/micro-organisms
[8] http://admin.indiaenvironmentportal.org.in/category/thesaurus/health-care
[9] http://admin.indiaenvironmentportal.org.in/category/thesaurus/diseases
[10] http://admin.indiaenvironmentportal.org.in/category/thesaurus/research
[11] http://admin.indiaenvironmentportal.org.in/category/thesaurus/united-states-america-us
[12] http://admin.indiaenvironmentportal.org.in/category/thesaurus/infectious-diseases
[13] http://admin.indiaenvironmentportal.org.in/category/thesaurus/antibiotic
