The World Health Organization estimates that > 140 million people worldwide are exposed to arsenic (As)–contaminated drinking water. As undergoes biologic methylation, which facilitates renal As elimination. In folate-deficient individuals, this process is augmented by folic acid (FA) supplementation, thereby lowering blood As (bAs). Creatinine concentrations in urine are a robust predictor of As methylation patterns. Although the reasons for this are unclear, creatine synthesis is a major consumer of methyl donors, and this synthesis is down-regulated by dietary/supplemental creatine.
Original Source [2]
Technology Partners: MimirTech
Links:
[1] http://admin.indiaenvironmentportal.org.in/feature-article/folic-acid-and-creatine-therapeutic-approaches-lower-blood-arsenic-randomized
[2] http://ehp.niehs.nih.gov/1409396/
[3] http://admin.indiaenvironmentportal.org.in/category/author/brandilyn-peters
[4] http://admin.indiaenvironmentportal.org.in/category/author/megan-n-hall
[5] http://admin.indiaenvironmentportal.org.in/category/author/xinhua-liu-et-al
[6] http://admin.indiaenvironmentportal.org.in/category/journal/environmental-health-perspectives
[7] http://admin.indiaenvironmentportal.org.in/category/thesaurus/arsenic
[8] http://admin.indiaenvironmentportal.org.in/category/thesaurus/drinking-water-quality
[9] http://admin.indiaenvironmentportal.org.in/category/thesaurus/nutrition
[10] http://admin.indiaenvironmentportal.org.in/category/thesaurus/bangladesh
[11] http://admin.indiaenvironmentportal.org.in/category/thesaurus/south-asia
[12] http://admin.indiaenvironmentportal.org.in/category/thesaurus/research
[13] http://admin.indiaenvironmentportal.org.in/category/thesaurus/groundwater-pollution
[14] http://admin.indiaenvironmentportal.org.in/category/thesaurus/health-effects
