Chrysotile asbestos accounts for more than 90% of the asbestos used worldwide and exposure is associated with asbestosis (asbestos-related fibrosis) and other malignancies, but the molecular mechanisms involved are not fully understood. A common pathogenic mechanism for these malignancies is represented by epithelial-mesenchymal transition (EMT), through which epithelial cells undergo a morphological transformation to take on a mesenchymal phenotype.