There is significant scientific evidence indicating that the global climate is changing, largely due to human activities. Such climatic fluctuations may adversely impact human health and well-being in a variety of ways, including through exposure to extreme weather events; disruption of ecosystems, agriculture, and food production; expansion of infectious diseases; and increased levels of harmful air particulates. New research seeks to provide a deeper understanding of the health consequences of climate change on humans — including better quantification of these effects — to improve health preparedness and protect vulnerable populations.