Zika virus (ZIKV), an emerging flavivirus, generally causes mild infection in humans but is associated with severe neurologic complications and adverse fetal outcomes. ZIKV is transmitted to humans primarily by aedes mosquitoes. However, there is some evidence of sexual transmission. Two studies have shown the presence of infectious ZIKV in semen. A recent article described detection of ZIKV RNA in semen 62 days after the onset of illness, but infectious virus was not cultured.