Medicinal plants mentioned in Ayurveda can be used as food or medicine due to their impact on human health and disease prevention. For example, Guduchi has been used as an immunomodulator for its ability to enhance the immune response. In the present study, fresh juice extracts of Brahmi and Guduchi was evaluated for its immunomodulatory and antioxidant activity. Fresh juice of Brahmi and Guduchi was prepared and lyophilized.