In order to make a scientific emergency strategic decision after an earthquake, casualties need to be estimated rapidly. Asia is the most earthquake-prone continent in the world. In this paper, by spatial statistic and regressive analysis of historical Asian earthquake data from 1990 to 2012, vulnerability curves portraying the empirical relationship between the magnitude of an earthquake event and the casualty rate caused by it were created for countries of six-groups and the Quick Assessment Model of Earthquake Casualties for Asia (QAMECA) was developed.