The Union health ministry will set up a vaccine manufacturing unit with World Health Organisation's licence and a medical park at Chengalpattu, 30 km from Chennai, at an investment of Rs 300 crore to Rs 500 crore. Speaking to reporters in Chennai on Saturday, Union Health Minister Anbumani Ramadoss said the upcoming vaccine unit and the medical park, along with a medicity and research and development (R&D) centre, would centralise the vaccine production in the country.