To provide alternatives to petroleum-based energy, enhance global security, and reduce carbon emissions, the U.S. government has mandated a greater proportion of energy portfolio be derived from plant-based fuels (i.e., 2007 Energy Independence and Security Act; EISA). However, the potential benefits of this nascent bioeconomy may be offset by damage to biosecurity via land-use change, inappropriate agronomics, rapid adoption of novel crops, and/or lack of proper federal oversight.