Kyasanur Forest disease virus (KFDV) was first identified in 1957, when it was isolated from a sick monkey from the Kyasanur Forest in Karnataka State, India. Since then it has been reported to be enzootic in five districts of Karnataka State. Despite the availability of a vaccine against the disease, reports of human infections are on the rise. Isolated cases and antibody against KFDV have been reported from new areas from the states of Tamil Nadu, Maharashtra and Kerala in India. Here, we report the features of the first outbreak of Kyasanur Forest disease (KFD) from Kerala involving 184 cases and 9 deaths.

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