The present study assess spatial change in the land cover over the last decade in Pranahita Wildlife Sanctuary, Adilabad district, Andhra Pradesh, India using Landsat TM and IRS P6 LISS III images. From 1993 to 2004, the forest cover had a severe change and lost about 248.87 ha. There was increase in the scrub cover to about 1637.17 ha, which was quantified to be 172.77 ha.