This study presents adsorption performances for Carbamazepine, Propyphenazone and Sulfamethoxazole using polymer resin, Lewatit VP OC 1163. Adsorption capacities followed: Carbamazepine>Sulfamethoxazole>Propyphenazone. Lewatit VP OC 1163 showed a larger adsorption for pharmaceuticals having low solubility, with Freundlich adsorption parameter, Kf, reaching 46.068 for Carbamazepine.