Dietary supplements, including vitamins and herbal products, are often used to treat self-diagnosed conditions and/or to promote health. We conducted a community-based survey in a rural population to assess consumers’ knowledge, practices, and attitudes regarding the use of dietary supplements. A total of 526 adults (≥ 18 years) completed the survey. Information collected included product(s) used, frequency and use in combination with prescription or over-the-counter medications, and perceptions of efficacy and safety.