The year 1980 has often been used as a benchmark for the return of Antarctic ozone to conditions assumed to be unaffected by emissions of ozone depleting substances (ODSs), implying that anthropogenic ozone depletion in Antarctica started around 1980. Here, the extent of anthropogenically-driven Antarctic ozone depletion prior to 1980 is examined using output from transient Chemistry-Climate Model (CCM) simulations from 1960 to 2000 with prescribed changes of ozone depleting substance concentrations in conjunction with observations.