Epizootic ulcerative syndrome (EUS), a disease listed by World Organisation for Animal Health (OIE) has been reported in 26 countries across 4 continents. Till date, 94 fish species have been fouund to be naturally infected with EUS and its host range is gradually expanding. In the year 2010-11, outbreaks resulting in heavy fish mortality were recorded in wetland districts of Uttar Pradesh, India and EUS was confirmed as the cause of mortality.