With the Millennium Development Goals (MDGs) expiring in 2015, the world awaits a new, ambitious framework for improving lives. This framework must pass the vital test of reducing inequalities, especially gender-related ones, as a critical step towards the improvement of women's health. Measurably improving women's health throughout the life course will contribute to other post-2015 goals. Conversely, women's social empowerment through education, participation in the labor market, and political representation will improve health.