The heritage landscape of Burhanpur has an architectural and horticultural composition, consisting of many historic gardens, a unique water management system, a sustainable planning and design framework, the use of landscape and topography with numerous heritage components and historical monuments, temples, tombs and mosques that are locally, regionally and nationally significant. Conserving Burhanpur as an inspirational model for other sites is not only a cultural heritage objective, but it is also a crucial component of the heritage-based sustainable regeneration of the landscape, because it is directly linked to environmental integrity, economic efficiency and resources for present and future generations. Although the last decade has witnessed vigorous efforts by the municipal corporation to preserve and develop Burhanpur by designating it as one of the heritage cities of the UNESCO—Indian Heritage Cities Network (in 2006), a coherent, holistic and sustainable heritage outcome has not been achieved. This paper proposes to harness the cultural landscape as an approach for the sustainable regeneration of Burhanpur heritage and takes a holistic approach to the interpretation of the historic district and natural landscape of the city, where historic buildings are located.