The report analyzes the characteristics of global extreme weather disasters from 2000 to 2021. During this period, annual direct economic losses from extreme disasters in Asia, America, Europe and Africa showed an increasing trend. The frequency of such disasters was far higher in Asia than on other continents, and the total losses in Asia from 2011 to 2021 were twice those of Asia from 2000 to 2010. The report also summarizes the characteristics of global climate, and the major weather and climate events in 2021, coupled with an analysis of the causes of typical major weather and climate events, including rainstorm-induced flood, drought, tropical cyclone, heat wave and wildfire, cold wave and severe convection. The report calls for greater world attention to tackling increasingly frequent extreme weather and climate events, and boosting collaborative research toward that end.