The Karakoram and the Himalayan mountain range accommodate a large number of glaciers and are the major source of several perennial rivers downstream. To interactively describe to response of glaciers to climate change, a glacier parameterization scheme has been developed and implemented into the regional climate model REMO. The scheme simulates the mass balance as well as changes of the areal extent of glaciers on a subgrid scale. The parameterization scheme is for the first time applied to the region.