Approaches to integrated landscape management are currently garnering new interest as scientists, policymakers, and local stakeholders recognize the need to increase the multi-functionality of agricultural landscapes for food production, livelihood improvement, and ecosystem conservation. Such approaches have been attempted in many parts of Latin America and the Caribbean (LAC) but to date there has been no systematic assessment of their characteristics, outcomes, and limitations. To fill this gap, we surveyed participants and managers in integrated landscape initiatives throughout the LAC region to characterize these initiatives’ contexts, motivations and objectives, stakeholders and participants, activities and investments, outcomes, and major successes and shortcomings. Results from 104 initiatives in 21 countries indicate that integrated landscape management is being applied across the region to address a variety of challenges in diverse contexts, and that use of this approach is expanding.