Due to high levels of poverty, all of Mali’s territory and population could be said to be highly vulnerable to future climate change. In spite of the fact that Mali, like its Sahelian neighbors, has a long history of coping with climate variability — and its livelihood systems are diversified in such a way as to reduce risk — the country has higher levels of overall vulnerability as compared to countries with higher levels of income and more stable/humid climates. The purpose of this mapping exercise is to highlight hotspots of particularly high relative vulnerability within Mali due to constellations of high climatic stress, high sensitivity (or susceptibility), and low adaptive capacity.