This paper outlines IFAD’s strategic approach to enhancing food security and promoting sustainable smallholder agriculture development in Small Island Developing States (SIDS) in the context of exacerbated impacts of climate change and persistent challenges to market access. A renewed approach will provide an opportunity for increasing results and impacts from agriculture and fisheries, reducing the high transaction costs of project delivery in SIDS, adjusting to an ever-changing development environment and – most of all – avoiding the overlooking of SIDS’ persistent fragility and the risk that they are cut off from development assistance.