This report provides accountability for the 3 Global Health Sector Strategies (2016-2021) on HIV, Viral Hepatitis and the STIs. The report assesses the impact, progress and gaps, and identifies actions to improve impact. The report also provides new data to assess the achievement of the SDGs targets and gaps towards the Thirteenth General Programme of Work (GPW 13) targets and a decade towards elimination. The report describes WHO’s important contributions at regional and global level and identifies common actions across the 3 disease areas as well as gaps and priorities as a baseline for the next strategies.