Water security is recognized as one of the great challenges of the 21st century. The triple decline in quantity, quality, and reliability of potable freshwater poses numerous serious problems. The purpose of this publication is to highlight the importance of safeguarding nature in order to secure water-related services, and to achieve the Sustainable Development Goals. This publication serves as a call to action, to governments, to land use planners, to corporations, and to citizens everywhere to take urgent action to secure nature for life.