Transforming care for the 30 million vulnerable newborns who are currently being left behind is a smart investment in the health and development of future generations. It will also significantly move us along the path to achieving the United Nations Sustainable Development Goals (SDGs), through universal health coverage (UHC), by 2030. The Key Findings report, Survive and thrive: transforming care for every small and sick newborn, provides an overview of what will be presented in the full report. It outlines the global problem, showcases the progress, summarizes what can be done to transform inpatient care for small and sick newborns, and demonstrates the importance of data to guide investment and improve quality and equity. It presents a clear call to action to accelerate progress towards the Sustainable Development Goals to ensure every newborn has the chance to live a healthy and productive life.