With a growing global population, the absolute numbers exposed to pollutants will increase unless urgent policies are implemented and actions taken on the ground. Pollution can have a particularly disproportionate and negative effect on the poor, the disadvantaged and the vulnerable. Consequently, pollution constitutes a significant impediment to achieving health, well-being, prosperity and the sustainable development goal to “leave no one behind”. Solutions and success stories abound to help clean up pollutants and detoxify our environment. Towards a Pollution-Free Planet is the theme of the 2017 UN Environment Assembly. UN Environment is preparing a report that will provide evidence of a polluted planet; describe how acting on pollution helps achieve the sustainable development goals; and discuss a framework for a global agenda to address pollution.