Tomato, cabbage, and garden egg are important crops for small-scale farmers and migrants in the rural and peri-urban areas of Ghana. Genetic modification has the potential to alleviate poverty through combating yield losses from pests and diseases in these crops, while reducing health risks from application of hazardous chemicals. This study uses farm survey data to gauge the potential for adoption of genetically modified varieties, estimate the potential impact of adoption on farm profits, and highlight economic differences among the three crops.